Best Motorcycle Riding Destinations in Missouri

If you’re a motorcycle rider, one of the best states to ride a motorcycle is Missouri. Known as "The Show-Me State," Missouri is famous for its breathtaking scenery—and that extends to its incredible motorcycle rides. From the rolling hills of the Ozarks to the lush forests of the Mark Twain National Forest, motorcycle riders can enjoy landscapes and thrilling open roads.

In Missouri, iconic routes like Route 66 give a nostalgic journey through America's heartland, while the state's varying topography offers both leisurely cruises and adrenaline-pumping challenges. With a landscape that offers scenery, rich American history, and routes for riders of all skill levels, Missouri is a must-go for motorcycle riders! Today, we've put together a list of some of the best roads to explore on your next ride through the state.

Pro Tip: Missouri’s climate can be hot and humid, especially in the spring, summer, and fall. Be sure to pack breathable riding gear for those warmer months. While the state is filled with beautiful riding weather, it's also home to severe thunderstorms and tornadoes, so stay updated on weather alerts to ensure a safe journey.

1. Route 66: St. Louis to Grey Pass Summit

This classic stretch of Route 66 offers riders the chance to experience historic Midwestern scenery and landmarks. The road runs parallel to I-270 and crosses the Miramac River, providing plenty of opportunities to soak in Missouri’s culture. For a fun detour, stop by Six Flags and make it a full day of adventure.

2. The Lazy 8

This 50-mile stretch along Highway 8 takes you from Park Hills through the Mark Twain National Forest into mining country. It’s a great route for all experience levels, offering a mix of smooth riding with just enough technical challenges to keep things interesting. Along the way, stop by the St. James Winery or explore the scenic pull-offs.

3. Highway 94: Weldon Spring to Augusta

Highway 94 offers a sweeping 70-mile ride through Missouri’s backcountry. With lush scenery, hiking and biking trails, and peaceful fishing spots, this route is perfect for those who love the great outdoors. Pack a lunch, as there are few places to stop along the way, but the solitude and beauty make it worth the trip.

4. Wing of the Dragon (Route 185)

If you’re up for a challenge, Route 185, known as the Wing of the Dragon, is your road. This thrilling route offers sharp turns, steep climbs, and quick drops in elevation, making it a high-speed adventure. It's not for the faint of heart, but experienced riders will relish the intensity of this ride.

5. Tail of the Newt (Highway 45)

Another reptilian-inspired route, the Tail of the Newt, offers a more laid-back but still engaging ride through Missouri’s farm country. Enjoy the smell of tobacco, corn, and soybeans as you wind through gentle curves and dips. End your ride in Parkville for some delicious barbecue—it's a must!

6. Chamois to Mount Sterling

This 20-mile ride along the Missouri River is perfect for those who appreciate rural landscapes. The road can be a bit tricky after a storm, but that just adds to the thrill. Experienced riders will enjoy the winding turns and the peaceful, sparsely populated surroundings.

7. Missouri Wine Country Tour

Travel 60 miles through the Missouri River Valley, surrounded by postcard-worthy farms, limestone bluffs, and plenty of wineries. Stop by charming towns along the way, and if you're visiting in the fall, don’t miss the Oktoberfest in Hermann. It's a relaxing ride with plenty of opportunities to explore local history and culture.

8. Ride the Eagle (Missouri Route 86)

This hidden gem takes you through Ozark country with rolling hills, banked turns, and vibrant foliage. The 24-mile ride from Eureka Springs, Arkansas, to Cassville, Missouri, is a scenic adventure, especially in the fall. It’s a smooth ride on well-maintained roads with light traffic—perfect for a laid-back day on your bike.

9. The Big Mo River Ride Loop

This 123-mile loop offers cool, refreshing views of the Missouri River. With plenty of stops along the way, you can explore historical sites like the Battle of Lexington State Historic Site and the Ray County Museum. It’s a leisurely ride with a mix of natural beauty and fascinating history.

Enjoy the Best Motorcycle Riding Destinations in Missouri

At Harley-Davidson, we’re always on the lookout for the best motorcycle rides in the state, and we love sharing our favorites with you. If your bike is collecting dust in the garage, it’s time to hit the open road and explore all that Missouri has to offer.

If you are in MO, stop by our Blacktop Harley-Davidson dealership in Columbia, Missouri to check our brand new and pre-owned motorcycles. If you also want a tune-up, some new gear, or just to chat about your latest ride, our team at Blacktop is here to help you make the most of your Missouri motorcycle adventures!